Key takeaways

  • Ebglyss (lebrikizumab-lbkz) is not known to interact with alcohol, other medications, or supplements. But it’s important to discuss all substances you take and any health conditions you may have with your doctor before starting this medication.
  • Live vaccines should be avoided during Ebglyss treatment. This is to minimize the risk of infection because Ebglyss may impact how your immune system responds to infections.
  • People with parasitic infections or eye problems should consult their doctor before starting Ebglyss, as the drug’s effects on these conditions are not fully known.

Ebglyss is used in adults and certain children to treat moderate to severe atopic dermatitis.

An interaction can occur because one substance causes another substance to have a different effect than expected. Interactions can also occur if you have certain health conditions. Keep reading to learn about Ebglyss’s possible interactions.

Ebglyss isn’t known to interact with other drugs. The manufacturer did not look at interactions in the drug’s studies.

However, interactions with other medications could be recognized in the future. For example, new interactions could be reported by people who’ve used Ebglyss since it was approved.

Before you start treatment with Ebglyss, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions.

To learn whether Ebglyss interacts with herbs, vitamins, or supplements, see the “Are there other interactions with Ebglyss?” section.

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

Certain health conditions or other factors could increase your risk of harm if you take Ebglyss. These are known as contraindications. In such cases, your doctor may not prescribe this medication for you. Ebglyss has one contraindication, which is a previous allergic reaction.

If you’ve had an allergic reaction to Ebglyss or any of its ingredients, your doctor likely won’t prescribe this medication for you. Ask them about other treatments that may be better options.

Ebglyss is not known to interact with alcohol. However, alcohol can trigger symptoms of atopic dermatitis in some people. Since Ebglyss is used to treat this condition, your doctor may recommend limiting or avoiding alcohol if you notice it worsens your symptoms.

If you have questions about consuming alcohol during Ebglyss treatment, talk with your doctor or pharmacist.

In rare cases, people taking Ebglyss developed antibodies to the drug itself. These didn’t seem to change how well the medicine worked or how safe it was, but your doctor may keep an eye on your response to Ebglyss treatment over time.

Ebglyss may have other interactions. Here are additional interactions that may occur with this medication. Note that this is not a full list of all other possible interactions with Ebglyss.

Does Ebglyss interact with supplements?

Before you start treatment with Ebglyss, talk with your doctor and pharmacist about any herbs, vitamins, or supplements you take. Sharing this information with them may help you avoid possible interactions.

Ebglyss and herbs

There are currently no reports of Ebglyss interacting with herbs. But this doesn’t mean that interactions with herbs won’t be recognized in the future. For this reason, it’s important to check with your doctor or pharmacist before taking any of these products during Ebglyss treatment.

Ebglyss and vitamins

There are currently no reports of Ebglyss interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future. For this reason, it’s important to check with your doctor or pharmacist before taking any of these products during Ebglyss treatment.

Does Ebglyss interact with food?

There are currently no reports of Ebglyss interacting with food. If you have questions about eating certain foods during your treatment with Ebglyss, talk with your doctor.

Does Ebglyss interact with vaccines?

You should not receive live vaccines during Ebglyss treatment.

Live vaccines contain weakened versions of the virus or bacteria they’re meant to protect against. Getting a live vaccine during Ebglyss treatment could increase your risk of infection.

Examples of live vaccines include measles, mumps, rubella (MMR), rotavirus, and chickenpox.

If you need to receive a vaccine, talk with your doctor first to make sure it’s safe.

Does Ebglyss interact with lab tests?

There are currently no reports of Ebglyss interacting with lab tests. If you have questions about having certain lab tests during your treatment with Ebglyss, talk with the healthcare professional ordering the test.

Does Ebglyss interact with cannabis or CBD?

There are currently no reports of Ebglyss interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But as with any drug or supplement, talk with your doctor before using cannabis with Ebglyss.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions or other health factors may raise the risk of interactions with Ebglyss. Before starting treatment with this medication, talk with your doctor about your health history. They’ll determine whether Ebglyss is right for you.

Health conditions or other factors that might interact with Ebglyss include:

Parasitic infection: Before starting Ebglyss, tell your doctor if you have or recently had a parasitic infection, such as intestinal worms. People with these infections were not included in the drug’s studies, so it’s not known whether Ebglyss could affect how your immune system responds to the infection.

Your doctor will treat any existing infection before you start Ebglyss treatment. If you develop a parasitic infection during treatment, your doctor can tell you whether it’s safe to continue Ebglyss treatment.

Eye problems: Before starting Ebglyss, tell your doctor if you have an eye condition. Ebglyss may cause eye problems, such as conjunctivitis or keratitis, as side effects. Your doctor can tell you whether Ebglyss is a safe treatment option. They may monitor the symptoms of your eye condition during treatment.

Pregnancy: It’s not known whether Ebglyss is safe to receive during pregnancy. If you’re pregnant or may become pregnant, talk with your doctor before starting this medication.

If you become pregnant during Ebglyss treatment, you’re encouraged to contact the drug manufacturer to report your experience. To learn more, call 800-545-5979 or talk with your doctor.

Breastfeeding: It’s not known whether it’s safe to receive Ebglyss while breastfeeding. It isn’t known if drug passes into breast milk or whether it may cause side effects in a child who is breastfed. If you’re breastfeeding or planning to breastfeed, talk with your doctor about your options.

Allergic reaction: If you’ve had an allergic reaction to Ebglyss or any of its ingredients, your doctor will likely not prescribe Ebglyss since the drug could cause another allergic reaction. You can ask them about other treatments that may be better for you.

Taking certain steps can help you avoid interactions with Ebglyss. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

  • whether you drink alcohol or use cannabis
  • the list of medications you take, as well as any vitamins, supplements, and herbs
  • what to do if you start taking a new drug during your Ebglyss treatment

It’s also important to understand Ebglyss’s label and other paperwork that may come with it. Colored stickers that describe interactions may be on the label. The paperwork, sometimes called the patient package insert or medication guide, may have other details about interactions.

If you did not get paperwork with Ebglyss, ask your pharmacist to print a copy for you. If you have difficulty reading or understanding this information, your doctor or pharmacist can help.

Using Ebglyss exactly as prescribed can also help prevent interactions.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.