The price you pay for Briumvi may depend on factors such as your treatment schedule, whether you have health insurance, and where you receive infusions. Financial assistance may be available to help with the cost.
Briumvi (ublituximab-xiiy) is a CD20-directed cytolytic antibody approved for treating relapsing forms of multiple sclerosis (MS) in adults. It is given as an intravenous (IV) infusion in an infusion center or hospital.
In MS, the immune system attacks the central nervous system, and Briumvi targets specific immune cells (B cells) to help slow this process.
Living with MS is stressful enough, but figuring out how to pay for treatments can make it even harder. This article explains the factors that affect the cost of Briumvi and the financial assistance programs available.
Because everyone’s treatment schedule and insurance coverage differ, the cost of Briumvi can vary.
What you pay for Briumvi depends on:
- whether you have health insurance or not
- your insurance plan
- whether you’re eligible for financial assistance programs
- the cost of receiving Briumvi at a hospital or infusion center
- your treatment schedule
- the pharmacy you use
- premedication costs
- monitoring costs
Most health insurance plans help cover MS treatments, but the amount they cover can vary. Your insurance company might require you to pay a copay (a flat fee) or coinsurance, which means you have to pay a certain percentage of the drug’s total price
Your doctor will help you complete, sign, and submit a form to get started with Briumvi patient support.
If you have insurance, your Briumvi case manager will contact your insurance company to gather coverage details and calculate your out-of-pocket (OOP) costs. They will also help find a nearby infusion center that accepts your insurance.
If you don’t have insurance, your case manager will assess your situation and explain how you can access help with Briumvi costs.
If you’re looking to connect with other people with MS, resources like Healthline’s Bezzy MS offer an online space for community, peer and expert guidance, and support.
Your Briumvi case manager will determine if you’re eligible for financial support. Available programs include:
Briumvi copay assistance program
Most people with private health insurance plans are eligible for the Briumvi copay assistance program. It covers treatment costs up to the annual maximum of $20,000.
It also covers infusion and administration costs up to $550 for the first infusion and up to $350 per infusion after that.
Briumvi patient assistance program
People without insurance or underinsured who meet certain financial eligibility criteria may qualify for the Briumvi patient assistance program.
Other support
Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Examples include:
The PAN Foundation offers a copay grant for people taking MS medications. In 2026, people who qualify can get a $2,700 starting grant and up to $5,400 per year to help pay for their out-of-pocket medication costs
The HealthWell Foundation assists people with Medicare with copays, premiums, and OOP expenses up to a maximum of $8,000. Your income must fall within 300% to 500% of the federal poverty level.
Briumvi is an IV medication for adults living with relapsing forms of MS. Because it requires administration by a healthcare professional and taking extra pre-medications, the costs can add up quickly.
Most private health insurance plans cover most of the costs of Briumvi. Your doctor can help connect you with Briumvi patient support. A case manager will liaise with your insurance company to work out your OOP costs and help keep your treatment on schedule.
You can also apply for grants from organizations like the PAN Foundation and HealthWell Foundation.
Disclaimer: While Healthline strives for factual, comprehensive, and current information, this article is not a substitute for a licensed healthcare professional’s expertise. Always consult a doctor before taking or discontinuing any medication. Drug information is subject to change and may not cover all uses, directions, precautions, warnings, interactions, reactions, or adverse effects. The lack of a warning does not guarantee a drug’s safety, effectiveness, or appropriateness for all patients or specific uses. Learn more about our approach to content integrity.