Prescription beta-blockers help lower the heart rate. “Natural beta-blockers” in common foods, herbs, and supplements may also help lower blood pressure.

Beta-blockers are prescription medications that stop the effects of epinephrine (adrenaline), which slows the heart and lowers blood pressure. They do this by blocking various beta receptors.

Some foods, herbs, and supplements can also act as “natural beta-blockers” by lowering blood pressure naturally, but their mechanisms of action may differ from those of traditional beta-blockers.

Natural does not always mean safe

Many studies on natural beta-blockers do not have conclusive results. To avoid adverse reactions and unwanted side effects, consult a doctor before changing your diet or adding supplements

“Natural beta-blockers” function in the body as beta-blockers typically do, by reducing inflammation and lowering blood pressure.

These nutrients can also reduce blood pressure in other ways, so it’s important to discuss them with your doctor.

1. Antioxidants

Many fruits, vegetables, and plant-based foods contain antioxidants, which are crucial in preventing inflammatory conditions and may also lower blood pressure.

A research review from 2018 shows that eating foods containing antioxidants, such as fresh fruits and vegetables, may help reduce blood pressure.

2. L-arginine

L-arginine is an amino acid that helps produce nitric oxide (NO), which can cause blood vessels to enlarge and may help lower blood pressure.

It relaxes smooth tissue cells in the walls of blood vessels, which may lower blood pressure. This mechanism of lowering blood pressure is different from that of typical beta-blockers.

A 2021 research review shows that increased L-arginine levels are associated with lower blood pressure and anti-hypertensive effects.

Sources of L-arginine include:

  • meat and poultry
  • nuts and seeds
  • leafy vegetables

3. Potassium

Adequate potassium levels in the diet can help keep blood pressure levels low.

Many people get more than enough potassium from a balanced diet. Some sources of protein include:

  • low fat dairy products
  • fish
  • bananas
  • potatoes

The American Heart Association (AHA) recommends that adults consume between 2,600 milligrams (mg) and 3,400 mg of potassium daily.

Talk with your doctor before supplementing potassium instead of consuming it solely through diet, since some medications can also increase potassium.

Too much potassium can have harmful effects, including arrhythmias, especially in people with kidney disease or older adults.

4. Garlic (Allium sativum)

Researchers have studied garlic for many conditions, including high blood pressure and heart disease.

A 2019 research review citing older studies shows that garlic may effectively reduce blood pressure. It may also have similar benefits for other conditions that beta-blockers treat.

5. Hawthorn (Crataegus sp.)

Hawthorn is a traditional Chinese herb used to treat cardiovascular diseases.

A 2020 systematic review of people with mild hypertension (high blood pressure) suggests that hawthorn may have a positive effect on blood pressure in the short term.

Only limited studies are available at this time. Future trials are necessary to confirm these benefits in the long term.

6. Indian snakeroot (Rauwolfia serpentina)

Rauwolfia is a traditional herbal supplement for the treatment of hypertension. It contains tryptophan derivatives called indole alkaloids.

While more recent research is necessary, this herb may help lower blood pressure by reducing the body’s ability to absorb the neurotransmitter norepinephrine, which contributes to the body’s fight-or-flight response.

But Rauwolfia can have adverse side effects, including lethargy, hypotension, and vomiting.

It’s important to discuss Rauwolfia with your doctor before starting.

7. Red yeast rice (Monascus purpureus)

Red yeast rice is an herbal supplement for cardiovascular disease. It contains molecules called monacolins.

Monacolin K, in particular, works much like a statin and is the most well-studied compound in red yeast rice.

A 2023 research review found that red yeast rice is an effective option for lowering lipid levels in people with hypercholesterolemia, or high cholesterol levels in the blood.

Consult with your doctor before taking red yeast rice since it may have side effects similar to those caused by statin drugs.

8. Barberry (Berberis vulgaris)

Barberry is a traditional herbal medicine that may help treat inflammatory and cardiovascular conditions.

But research from past randomized controlled trials on whether barberry can lower blood pressure is mixed. More research is necessary before drawing any conclusions.

Some supplements may be beneficial for heart health. The following supplements work differently than typical beta-blockers.

9. Omega-3 fatty acids

Omega-3 fatty acids are polyunsaturated fatty acids that researchers have studied for their role in heart health.

These “healthy fats” may help reduce:

  • blood pressure
  • blood clots
  • high triglycerides and plaque deposits
  • inflammation

One review of randomized controlled trials found that EPA and DHA, two types of omega-3s, may effectively lower blood pressure when taken at 2 to 3 grams (g) per day.

Dosages higher than this may also benefit those at high risk for heart diseases.

10. CoQ10 (coenzyme Q10)

Coenzyme Q10 plays an important role in energy production and antioxidant protection. Low levels of CoQ10 have been linked to various diseases, including Parkinson’s and Alzheimer’s.

A 2022 systematic review of randomized controlled trials found that CoQ10 supplementation modestly reduced systolic blood pressure in people with cardiometabolic disorders.

11. Magnesium

Magnesium is essential for metabolic processes such as muscle contraction and nervous system regulation. Low magnesium levels may lead to high blood pressure.

A 2020 research review suggests that magnesium may protect against hypertension.

Speak with your doctor if you are considering taking magnesium or any other supplements.

Eating more fruits, vegetables, and antioxidant-rich foods has few risks, but speak with a doctor if you’re considering changing your diet or supplementation.

Some herbal supplements may interact negatively with medications. Consult your doctor before starting any supplement, especially if you take prescription medications.

Never stop taking your prescription beta-blockers or other medications without your doctor’s approval.

Talk with your doctor about other nutrition and lifestyle changes that can help to reduce your blood pressure naturally.

Beta-blockers are a commonly prescribed medication for conditions such as high blood pressure and anxiety. They function by reducing the effects of adrenaline on the heart.

Natural beta-blockers, found in many fruits, vegetables, and supplements, function similarly by reducing blood pressure but may have different mechanisms of action.

These natural beta-blockers, such as garlic, red yeast rice, and barberry, may also improve your overall heart health. Consider eating more of or supplementing with these natural options.

As with any new dietary changes, always consult your doctor first.