Lybalvi (olanzapine/samidorphan) is a prescription oral tablet used to treat schizophrenia and bipolar 1 disorder in adults. Lybalvi’s cost may depend on factors including whether you have health insurance and which pharmacy you use.

The price you pay for Lybalvi can vary. Your cost may depend on factors such as:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • available financial assistance for Lybalvi, such as whether you qualify for the Lybalvi Co-Pay Savings Program (see the “Financial and insurance assistance” section)

To find out how much you’ll pay for Lybalvi, talk with your doctor, pharmacist, or insurance provider.

Coupons and savings

You may be able to find drug coupons on prescription discount websites that can reduce the cost of your medication. These coupons cannot be used with insurance copays or benefits, but the discounted price may be lower than what you would pay through insurance.

Lybalvi only comes as a brand-name drug. It’s not currently available in a generic version. A generic contains an exact copy of the active ingredient in a brand-name medication but tends to cost less.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you take Lybalvi long term, you may be able to lower your costs in the following ways:

Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of Lybalvi if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Lybalvi. If you’re interested in getting a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.

Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for Lybalvi. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Lybalvi or help understanding your insurance coverage, assistance is available. For example:

  • A Lybalvi Co-Pay Savings Program is available for people with insurance. For more information and to find out whether you’re eligible for support, call 855-820-9624 or visit the program website.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

Here are answers to some frequently asked questions about Lybalvi’s price.

How does the cost of Lybalvi compare with that of similar drugs, such as Abilify?

The cost of Lybalvi compared with the cost of other drugs such as Abilify (aripiprazole) can depend on several factors.

For example, the form of the drug your doctor prescribes may affect the cost. Both Lybalvi and Abilify come as oral tablets. But Abilify may also be given as an injection into a muscle by a healthcare professional.

Other factors that may affect how much you pay include:

  • whether there are any savings programs available for the drug you’re prescribed
  • whether you have insurance or are paying out of pocket
  • how long your treatment lasts

If you have questions about the cost of Lybalvi compared with the cost of similar medications, talk with your doctor, pharmacist, or insurance provider. They can share more details on treatment costs based on your specific situation.

How much does Lybalvi cost with insurance vs. without it?

What you pay for Lybalvi if you have insurance compared to what you’d pay without it depends on several factors.

Factors that could affect what you pay for this drug without insurance include:

  • your treatment plan and dosage
  • whether you apply and qualify for any savings programs
  • the pharmacy you choose
  • the supply of medication you’re prescribed (such as a 30-day or 90-day supply)

These same factors may affect your price for Lybalvi if you have insurance. But the price you pay with insurance will also depend on:

  • your specific plan benefits
  • any prior authorization requirements you have for drug coverage

To learn more about what you’d pay for Lybalvi with or without insurance, talk with your doctor, pharmacist, or insurance provider (if you have one).

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If you have insurance, you may need to get prior authorization before your insurance provider will cover Lybalvi. This means your insurer and your doctor will discuss Lybalvi in regard to your treatment. Then, the insurance company will determine whether the drug is covered. If Lybalvi requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Lybalvi requires prior authorization.

If you still have questions about the cost of Lybalvi, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual price you’d pay for Lybalvi.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Will my dosage of Lybalvi affect the cost?
  • Are there lower cost drugs available to treat my condition?
  • What options do I have if I can’t afford Lybalvi?

To learn more about Lybalvi, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.