There’s no evidence that Skyrizi, the branded form of the drug risankizumab, can cause cancer. However, it may cause some other side effects, including:
- Hypersensitivity reactions: If you’re allergic to Skyrizi or any of its ingredients, you may experience hypersensitivity reactions, including anaphylaxis — a severe allergic reaction. These might come along with chest tightness, difficulty breathing, and skin rashes.
- Increased risk of infection: Skyrizi may increase your chances of getting certain infections, especially upper respiratory infections. This is because the drug can lower your immune system and make you more prone to viruses.
- Liver damage: Hepatotoxicity may occur when Skyrizi is used to treat inflammatory bowel disease (IBD).
Some people may believe that Skyrizi could cause cancer because it works to suppress your immune system. However, there are no warnings, indications, or evidence that Skyrizi can contribute to cancer development.
For example, some 2021 research looked at the risk of developing melanoma when using drugs like risankizumab to treat psoriasis. The researchers found no substantial risk.
According to some 2020 research, risankizumab, the generic form of Skyrizi, is generally well-tolerated for both short-term and long-term treatment. However, like any medication, it can have some side effects.
According to some 2019 research, the most common side effects of Skyrizi include:
- upper respiratory infections
- headache
- fatigue
- fungal infections
- irritation at the injection site
More serious side effects can occur. If you experience serious side effects, seek medical attention immediately. These include:
- liver damage
- allergic reactions
- serious infections like pneumonia
If you have any infections before starting Skyrizi, let your doctor know. They may delay starting the medication until your infection has cleared up.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.